IHI Trigger Tool for Measuring Adverse Drug Events

Aug 25, 2025

The use of “triggers,” or clues, to identify adverse drug events (ADEs) is an effective method for measuring the overall level of harm from medications in a healthcare organization. The Trigger Tool for Measuring Adverse Drug Events and the Adapted Trigger Tools provide instructions for conducting a retrospective review of patient records using a known list of ADE triggers and instructions for measuring the degree of harmful medication events to guide quality improvement efforts.